A zebrafish homologue of the murine Hox‐2.1 gene

FEBS Letters

Fjose, Anders¹  Molven, Anders¹  Njølstad, Pål R.¹ 

[1] Laboratory for Biotechnology, University of Bergen, PO Box 3152, Årstad, N-5029 Bergen, Norway

关键词: Homeobox;    Protein homology;    Embryogenesis;    (Brachydanio rerio);   

DOI  :  10.1016/0014-5793(88)80634-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Homeobox-containing sequences were isolated from a genomic library of zebrafish (Brachydanio rerio). A λ clone containing two homeobox cross-hybridizing regions was characterized. DNA sequencing of one of these regions (ZF-21) revealed that it contains a homeobox closely related to the Antennapedia class of Drosophila homeobox sequences. Moreover, the deduced amino acid sequence of the C-terminal end (81 residues including the homeobox) is identical to the corresponding part of the murine Hox-2.1 protein. Similar to Hox-2.1, a ZF-21 derived transcript of 2.3 kb is present in embryos at the somite forming stages.

【 授权许可】

Unknown