Antimicrobial properties of peptides from Xenopus granular gland secretions

FEBS Letters

Zasloff, Michael¹  Soravia, Emilia¹  Martini, Giuseppe¹ 

[1] Human Genetics Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA

关键词: Antimicrobial peptide;    Magainin;    Antibiotic;    (Xenopus);   

DOI  :  10.1016/0014-5793(88)80027-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Previously, we described a family of novel broad spectrum antimicrobial peptides, magainins, from the skin of Xenopus laevis. In this report we show that at least two other Xenopus peptides, present in the skin and its secretions, PGLa and a peptide released from the xenopsin precursor, exhibit antimicrobial properties comparable to the magainins. The identification of these newer members provides insight into the structural diversity of vertebrate antimicrobial peptides.

【 授权许可】

Unknown