The influence of the chain length of aldehydes on the fluorescence of chromolipids

FEBS Letters

Bezstarosti, K.¹  Groh, M.M.J.¹  Montfoort, A.¹  Koster, J.F.² 

[1] Department of Pathology I, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands;Department of Biochemistry I, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands

关键词: Chromolipid;    Malondialdehyde;    Aldehyde;    Chain length;   

DOI  :  10.1016/0014-5793(87)80559-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Incubation of phosphatidylethanolamine containing liposomes with malondialdehyde and other aldehydes with different chain lengths results in the fluorescence of chromolipids. Relative to malondialdehyde, the fluorescence was greatly enhanced with increasing chain length upon incubation of 2-alkenals with phospholipids. Similar results were found using the total lipid extracted from erythrocyte ghosts. It seems that the hydrophobic character of the aldehydes is important for the amount of fluorescence detected in lipid bilayers.

【 授权许可】

Unknown