The Effect of Astaxanthin and Regular Training on Dynamic Pattern of Oxidative Stress on Male under Strenuous Exercise

1st Annual Applied Science and Engineering Conference

工业技术;自然科学

Sylviana, N.^1 ; Gunawan, H.^1 ; Lesmana, R.^1 ; Purba, A.^1 ; Akbar, I.B.^2

Departement of Anatomy, Physiology Amd Cell Biology, Faculty Medicine, Universitas Padjadjaran, Indonesia^1

Department of Physiology, Faculty Medicine, Universitas Islam Bandung, Indonesia^2

关键词: Dynamic patterns;    Human bodies;    Lipid peroxidation;    Malondialdehyde;    Oxidative damage;    Physical activity;    Potent antioxidants;    Reactive oxygen species;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/180/1/012173/pdf
DOI  :  10.1088/1757-899X/180/1/012173

来源: IOP

【 摘 要 】

Strenuous physical activity will induced higher Reactive Oxygen Species (ROS) level in human body that can be measured by serum Malondialdehyde (MDA) level. Malondialdehyde is product of lipid peroxidation process that define as oxidative damage of lipid biomolecule by reactivity of reactive oxygen species. Still, the dynamic pattern of Malondialdehyde (MDA) level under strenuous exercise is not fully understood. Potent antioxidant such as Astaxanthin and training may be altered the level of MDA. Thus, purpose of this study is to understand effect of astaxanthin to MDA dynamic pattern on training male after strenuous physical activity. It was a double blind, experimental study, conducted on thirty young male age, divided into untrained and trained groups. Supplement Astaxanthin was given to 15 subject as well as placebo for one week after supplementation, Subjects were tested with anaerobic strenuous physical activity. The values were analyzed with ANOVA test followed by Duncan test showed that in every groups, mean of MDA before test was similar, start increase significantly after tested, begin decrease at 6thhour post test and back to baseline at 24thhour post-test (p