Cyclic GMP phosphodiesterase from bovine retina Amino acid sequence of the α‐subunit and nucleotide sequence of the corresponding cDNA

FEBS Letters

Ischenko, K.A.¹  Ovchinnikov, Yu.A.¹  Shuvaeva, T.M.¹  Lipkin, V.M.¹  Zagranichny, V.E.¹  Gubanov, V.V.¹  Khramtsov, N.V.¹  Muradov, K.G.¹ 

[1] Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, ul. Miklukho-Maklaya, 16/10, 117871 GSP Moscow V-437, USSR

关键词: Cyclic GMP phosphodiesterase;    Amino acid sequence;    cDNA cloning;    Nucleotide sequence;    (Bovine retina);   

DOI  :  10.1016/0014-5793(87)80530-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The α-subunit primary structure of cyclic GMP phosphodiesterase has been determined by parallel analysis of the protein amino acid sequence and the corresponding cDNA nucleotide sequence. The enzyme α-subunit contains 858 amino acid residues, its N-terminal amino group being acetylated. The partial primary structure of the enzyme, β-subunit has also been elucidated. A significant homology has been found between the α- and β-subunits of cGMP phosphodiesterase.

【 授权许可】

Unknown