Enhanced metabolism of phosphatidylinositol in Candida tropicalis in association with filamentous growth caused by ethanol

FEBS Letters

Uejima, Yasuhide¹  Koga, Teiichiro¹  Kamihara, Teijiro¹ 

[1] Laboratory of Industrial Biochemistry, Department of Industrial Chemistry, Faculty of Engineering, Kyoto University, Kyoto 606, Japan

关键词: Fungal dimorphism;    Filamentous growth;    Phosphatidylinositol turnover;    Ethanol;    (Candida tropicalis);    PI;    phosphatidylinositol;    PC;    phosphatidylcholine;    PE;    phosphatidylethanolamine;    PS;    phosphatidylserine;    CL;    cardiolipin;    PA;    phosphatidic acid;   

DOI  :  10.1016/0014-5793(87)80026-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Candida tropicalis Pk 233 grows in filamentous form in ethanol-supplemented medium, and myo-inositol prevents the ethanol ettect [(1979) Bioch!em. Biophys. Res. Commun. 91, 351–355]. Cells, which were grown with ethanol to the log phase, exhibited an increased rate of phosphatidylinositol turnover as judged by pulse-chase experiments with ³²P_i. Such enhanced metabolism of phosphatidylinositol was not observed in fully developed filamentous cells at the stationary phase or in yeast-like cells which were grown without added ethanol or with ethanol plus myo-inositol. The metabolism of other phospholipids was not affected by ethanol.

【 授权许可】

Unknown