Regulation of glycerol 3‐phosphate oxidation in mitochondria by changes in membrane microviscosity

FEBS Letters

Rauchová, Hana²  Svobodová, Jaroslava¹  Amler, Evžen²  Drahota, Zdeněk² 

[1] Department of Microbiology, Faculty of Natural Sciences Charles University, 120 00 Prague 2, Czechoslovakia;Institute of Physiology, Czechoslovak Academy of Sciences, 142 20 Prague 4 Czechoslovakia

关键词: (Brown fat);    Mitochondria;    Glycerol 3-phosphate oxidation;    Oleic acid;    Limiting anisotropy Rotational relaxation time;   

DOI  :  10.1016/0014-5793(86)81328-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The inhibition of glycerol 3-phosphate oxidation by oleic acid correlates with changes in membrane microviscosity monitored by the steady-state fluorescence anisotropy of DPH. The dynamic measurements indicate that the changes of both the limiting anisotropy and rotational relaxation time occur in a concentration range where the enzyme activity is strongly inhibited.

【 授权许可】

Unknown