期刊论文详细信息
FEBS Letters | |
Tyrosine kinases in normal human blood cells | |
Varshney, Grish C.1  Phan-Dinh-Tuy, Françoise1  Kahn, Axel1  | |
[1] Inserm U 129, 24 rue du Fg St Jacques, 75674 Paris Cedex 14, France | |
关键词: (Platelet; Red blood cell); Tyrosine kinase; p60c-src; Band 3; Differentiation; | |
DOI : 10.1016/0014-5793(86)80873-0 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
The major tyrosine kinase from platelets was purified as a 51 kDa active enzyme which was shown to be a degradation product of the protooncogene product p60c-src. Immuno-depletion experiments using a monoclonal antibody recognizing p60c-src failed to remove band 3 phosphorylating activity from red blood cell membranes. The erythrocyte tyrosine kinase was not at all immunoprecipitated by this antibody under conditions where the platelet enzyme was immunoprecipitated.
【 授权许可】
Unknown
【 预 览 】
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RO201912020288363ZK.pdf | 672KB | download |