Demonstration of mRNAs for oxytocin and prolactin in porcine granulosa and luteal cells

FEBS Letters

Pitzel, Lutz²  Einspainer, Ralf¹  Wuttke, Wolfgang²  Scheit, Karl Heinz¹  Hagendorff, Gerd¹  Kardalinou, Efterpi¹  Preuß, Klaus-Dieter¹ 

[1] Max-Planck-Institut für biophysikalische Chemie. Abteilung Molekulare Biologie, 3400 GöttingenFRG;Abteilung für klinische und experimentelle Endokrinologie, UFK Universität Göttingen, Göttingen, FRG

关键词: Oxytocin;    Prolactin;    mRNA;    Hybridization;    (Granulosa cell;    Luteal cell);    Progesterone secretion;   

DOI  :  10.1016/0014-5793(86)81383-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The relative levels of mRNAs for relaxin, prolactin, inhibin and oxytocin have been measured in porcine granulosa as well as luteal cells by hybridisation to single-stranded synthetic DNA. The likelihood of a paracrine function of oxytocin and prolactin in the porcine ovary was inferred from the invitro effects of both both hormones on progesterone secretion of ovarian cells. Both hormones were found to inhibit progesterone secretion of luteal cells. In contrast, only prolactin but not oxytocin stimulated progesterone secretion in granulosa cells.

【 授权许可】

Unknown