Putrescine may be a natural stimulator of glucose‐6‐phosphate dehydrogenase

FEBS Letters

Dodds, R.A.¹  Bitensky, Lucille¹  Chayen, J.¹  Dunham, Jane¹ 

[1] Division of Cellular Biology, Kennedy Institute of Rheumatology, Bute Gardens, London W6 7DW, England

关键词: Putrescine;    Glucose-6-phosphate dehydrogenase;    (Osteoblast);    Ornithine decarboxylase;    Growth;   

DOI  :  10.1016/0014-5793(86)80579-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The possible relationship between pyridoxal phosphate-dependent ornithine decarboxylase (ODC) activity and glucose-6-phosphate dehydrogenase (G6PD) activity has been studied in the osteoblasts of the growthplate of metatarsals of rats fed a pyridoxine-deficient diet, which caused depressed G6PD levels. The G6PD activity was fully restored when it was assayed in the presence of putrescine. It is suggested that this relationship may account for the correlation generally found between growth and ODC activity.

【 授权许可】

Unknown