Osmotic effects on bacterial transport and energetics

FEBS Letters

Deutsch, Carol J.²  Erecińska, Maria¹ 

[1] Departments of Pharmacology, Biochemistry and Biophysics University of Pennsylvania, Philadelphia, PA 19104, USA;Departments of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA

关键词: P. denitrificans;    Volume regulation;    Ion transport;    Respiration regulation;   

DOI  :  10.1016/0014-5793(85)80892-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Paracoccus denitrificans suspended in media containing 20–300 mM NaCl swelled progressively as the salt concentration was decreased. The increase in intracellular water volume was accompanied by an enhancement of respiration and a stimulation of the rates of net potassium and α-aminoisobutyric acid accumulation. It is postulated that influx of water and consequent lowering of intracellular solute concentration trigger transport mechanisms which are destined to restore the original ion and metabolite balance. Since a number of transport reactions operate against the electrochemical gradient of their substrates, energy utilization increases. The increased ATP usage and lowering of [ATP] stimulates the activity of the respiratory chain and increases oxygen uptake and energy production.

【 授权许可】

Unknown