The effect of bilayer order and fluidity on detergent‐induced liposome fusion

FEBS Letters

Saez, R.¹  Alonso, A.¹  Goñi, F.M.¹ 

[1] Department of Biochemistry, Faculty of Science, PO Box 644, Bilbao, Spain

关键词: Membrane fusion;    Liposome;    Surfactant;    Membrane order;    Membrane fluidity;   

DOI  :  10.1016/0014-5793(85)80541-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Surfactants induce fusion (or increase in size) of sonicated liposomes. This phenomenon is enhanced by cholesterol and inhibited by the intrinsic polypeptide gramicidin A. By comparison with previous physical studies we conclude that liposome ‘fusion’ is facilitated when both fluidity and static order of the bilayer are high.

【 授权许可】

Unknown