The H+/O ratio of proton translocation linked to the oxidation of succinate by mitochondria

FEBS Letters

Krab, Klaas¹  Soos, Jozsef¹  Wikström, Mårten¹ 

[1] Department of Medical Chemistry, University of Helsinki, Siltavuorenpenger 10A, SF-00170 Helsinki, Finland

关键词: Brain-gut peptide;    Gastrointestinal peptide;    Amino acid sequence;    Neuropeptide;    C-terminal amide;   

DOI  :  10.1016/0014-5793(84)80598-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

In a recent communication Lehninger and co-workers (Costa L.E., Reynaferje B., and Lehninger A.L. (1984) J. Biol. Chem. 259, 4802-4811) reported values approaching 8 for the H⁺/O ratio of vectorial proton ejection from rat liver mitochondria respiring with succinate. Here we present a rigorous analysis of these measurements which reveals that they may significantly overestimate the true H⁺/O stoicheiometry.

【 授权许可】

Unknown