Analysis of an inhibin preparation reveals apparent identity between a peptide with inhibin‐like activity and a sperm‐coating antigen

FEBS Letters

Johansson, Jan¹  Cederlund, Ella¹  Sheth, Anil¹  Jörnvall, Hans¹ 

[1] Department of Chemistry I, Karolinska Instituted S-104 01 Stockholm, Sweden

关键词: Inhibin;    Seminal plasma;    Primary structure;    Structural comparison;   

DOI  :  10.1016/0014-5793(84)80904-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The amino acid sequence of a large form of inhibin-like peptide in human seminal plasma was determined, and compared with structures reported for similar inhibin preparations and a seminal plasma globulin. The data confirm and correlate previous reports on this form of inhibin-like peptide. The structural comparisons further suggest that the peptide is closely similar to or possibly identical to a sperm-coating antigen reported to be synthesized from prostatic epithelium. This may correlate with non-gonadal origins of inhibin-like material and will help to elucidate the biological roles of inhibin(s).

【 授权许可】

Unknown