Partial amino acid sequence of a human seminal plasma peptide with inhibin‐like activity

FEBS Letters

Chrétien, M.²  Sairam, M.R.¹  Seidah, N.G.²  Ramasharma, K.¹ 

[1] Reproduction Research Laboratory, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal H2W 1R7, Canada;Laboratories of Biochemical and Molecular Neuroendocrinology, Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal H2W 1R7, Canada

关键词: Inhibin;    Sequence;    Fragment;    Seminal plasma;    Composition;   

DOI  :  10.1016/0014-5793(84)80840-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

An extract of human seminal plasma was found to have inhibin-like activity. The active factor was purified to homogeneity by ion exchange chromatography, molecular sieving and high performance liquid chromatography. The purified material has a mass of approximately 5 kDa and is very basic. Amino acid analysis showed the presence of approximately 35 residues while the sequencing data allowed the determination of the N-terminal 31 amino acids. There is a possibility of an additional 2–4 residues at the C-terminus, which could not be determined.

【 授权许可】

Unknown