期刊论文详细信息
FEBS Letters | |
Induction of TNF‐like factor by murine macrophage‐like cell line J774.1 on treatment with Sarcophaga lectin | |
Natori, Shunji1  Itoh, Akira1  Iizuka, Keiko1  | |
[1] Faculty of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113, Japan | |
关键词: Tumor necrosis factor; Sarcophaga; lectin; Macrophage; J774.1; | |
DOI : 10.1016/0014-5793(84)80569-4 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
On stimulation with Sarcophaga lectin, the mouse macrophage-like cell line J774.1 secreted a factor like the tumor necrosis factor (TNF) into the culture medium. This factor was a protein with a molecular weight of 40000–45000, and was cytotoxic to L-929 cells, but not to normal embryonic fibroblasts. This factor was effective on both the ascites form and solid form of sarcoma 180 transplanted into ICR mice.
【 授权许可】
Unknown
【 预 览 】
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