The effect of insulin on Fru‐2,6‐P2 levels in human fibroblasts

FEBS Letters

Farnararo, Marta²  Bruni, Paola²  Vasta, Valeria²  D'Alessandro, Antonino¹ 

[1] Department of Gerontology, Florence University, Istituto di Chimica biologica, viale Morgagni 50, I-50134 Florence, Italy;Department of Biochemistry, Florence University, Istituto di Chimica biologica, viale Morgagni 50, I-50134 Florence, Italy

关键词: Human fibroblast;    Fructose 2;    6-bisphosphate;    Glycolysis;   

DOI  :  10.1016/0014-5793(84)80470-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We report that fructose 2,6-bisphosphate (Fru-2,6-P₂) levels in quiescent human fibroblasts stimulated with insulin treatment increase in a time- and dose-dependent manner. The biochemical role of the sugar phosphate in the cellular response to the hormone which controls carbohydrate metabolism and acts as mitogenic factor is discussed.

【 授权许可】

Unknown