Effect of heme on the activity of chick embryo liver mitochondrial δ‐aminolevulinate synthase

FEBS Letters

Borthwick, I.A.¹  Srivastava, G.¹  May, B.K.¹  Elliott, W.H.¹  Pirola, B.A.¹  Brooker, J.D.¹ 

[1] Department of Biochemistry, University of Adelaide, Adelaide, South Australia 5000, Australia

关键词: Heme;    Hemin;    δ-Aminolevulinate synthase;    Enyzme activity;   

DOI  :  10.1016/0014-5793(84)80099-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have examined the effect of heme on the activity of native δ-aminolevulinate synthase isolated from drug-induced chick embryo liver mitochondria. The enzyme was not inhibited by concentrations of heme up to 1nM and this finding makes it improbable that heme acts physiologically to control mitochondrial δ-aminolevulinate synthase activity.

【 授权许可】

Unknown