Synthesis of 2‐deoxyglucitol from 2‐deoxy‐D‐glucose by the fungus Puccinia graminis

FEBS Letters

Manners, J.M.¹  Scott, K.J.¹  Maclean, D.J.¹ 

[1] Department of Biochemistry, University of Queensland, St. Lucia, QLD 4067, Australia

关键词: Puccinia;    Rust;    2-Deoxyglucose;    2-Deoxyglucitol;    2-Deoxygluconate;    Glucitol;    2-dG;    2-deoxy-D-glucose;    2-dGol;    2-deoxy-D-glucitol;    2-dGate;    2-deoxy-D-gluconate (lactone or open chain forms unspecified);   

DOI  :  10.1016/0014-5793(83)80931-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

After incubation of glucose-grown mycelium of Puccinia graminis with 2-deoxy-D-[U-¹⁴C]glucose, all cellular ¹⁴C was present in compounds soluble in 80% (v/v) ethanol. Metabolites identified included 2-deoxyglucitol, and free and phosphorylated forms of 2-deoxyglucose and 2-deoxygluconate. This is the first report of 2-deoxyglucitol as a metabolite of 2-deoxyglucose in any organism, and in P. graminis, this confirms previous proposals that the free D-glucose is directly reduced to D-glucitol in vivo.

【 授权许可】

Unknown