Rapid stopping of A23187 action by phosphatidylcholine

FEBS Letters

Lee, Jean W.¹  Vidaver, George A.¹ 

[1] Department of Chemistry, University of Nebraska, Lincoln, NE 68588-0304, USA

关键词: Ca2+ flux;    A23187 removal;    Phospholipid;    Erythrocyte;   

DOI  :  10.1016/0014-5793(83)80221-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The action on pigeon erythrocytes of the Ca²⁺ ionophore, A23187, can be nearly completely stopped within 30 s by treatment with a phosphatidylcholine dispersion at 39°C. A time-limited ⁴⁵Ca²⁺ uptake pulse can be produced by treating cells sequentially with A23187 and lipid, and the time-course of expulsion of this ⁴⁵Ca²⁺ uptake pulse can be easily determined.

【 授权许可】

Unknown