Monoclonal antibodies directed to human insulin‐like growth factor I (IGF I)

FEBS Letters

Binz, Hans¹  Baier, Wolfgang²  Humbel, René E.³  Laubli, Urs K.³  Celio, Marco R.² 

[1] Institut für Immunologie und Virologie der Universität, CH-8028 Zürich, Switzerland;Anatomisches Institut der Universität, CH-8006 Zürich Switzerland;Biochemisches Institut der Universität, CH-8028 Zürich Switzerland

关键词: Insulin-like growth factor;    Somatomedin;    Monoclonal antibody;    Radioimmunoassay;    Immunopurification;    High-performance liquid chromatography;   

DOI  :  10.1016/0014-5793(82)81082-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Mouse hybridomas secreting antibodies to human insulin-like growth factor I (IGF I) were produced by fusion of spleen cells of hyperimmunised mice with FO mouse-myeloma cells. Eight clones producing antibodies against human IGF I have been isolated, two of which have been characterised. One was used in a radioimmunoassay, the other for immunopurification of IGF.

【 授权许可】

Unknown