EFFICACY OF THE LOCAL ENDOMETRIAL INJURY IN PATIENTS WHO HAD PREVIOUS FAILED IVF-ICSI OUTCOME

Iranian journal of reproductive medicine

KARACAVUS S.¹  AYDIN TURGUT¹  KARA MUSTAFA¹  TURKTEKIN NURETTIN¹ 

关键词: LOCAL ENDOMETRIAL INJURY;    IN VITRO FERTILIZATION;    EMBRYO TRANSFER;    PREGNANCY;   

DOI  :  

学科分类：药学、药理学、毒理学（综合）

来源: Shahid Sadoughi University of Medical Sciences, Yazd

【 摘 要 】

Background: The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome.Objective: To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICSI cycle in patients who had recurrent IVF failure.Materials and Methods: An endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. The control group contained 42 women.Results: Implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant (p=001). Pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group (21.4%) (p=0.03).Conclusion: Local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent IVF-ICSI cycle in patients who had previous failed IVF-ICSI outcome.

【 授权许可】

Unknown