Assessment of Dose to the Nursing Infant from Radionuclides in Breast Milk

Leggett, Richard Wayne¹  Eckerman, Keith F¹ 

[1] ORNL

关键词: ADULTS;    BIOASSAY;    BODY BURDEN;    COMPUTERS;    EXCRETION;    FEEDING;    INGESTION;    LACTATION;    MAMMARY GLANDS;    MILK;    PARTICLE SIZE;    PLANNING;    PREGNANCY;    RADIATION PROTECTION;    RADIOISOTOPES;    SAFETY;   

DOI  :  10.2172/974621
RP-ID  :  ORNL/TM-2008/130
PID  :  OSTI ID: 974621
Others  :  TRN: US201008%%515

学科分类：生物科学（综合）

美国|英语

来源: SciTech Connect

【 摘 要 】

A computer software package was developed to predict tissue doses to an infant due to intake of radionuclides in breast milk based on bioassay measurements and exposure data for the mother. The package is intended mainly to aid in decisions regarding the safety of breast feeding by a mother who has been acutely exposed to a radionuclide during lactation or pregnancy, but it may be applied to previous intakes during the mother s adult life. The package includes biokinetic and dosimetric information needed to address intake of Co-60, Sr-90, Cs-134, Cs-137, Ir-192, Pu-238, Pu-239, Am-241, or Cf-252 by the mother. It has been designed so that the library of biokinetic and dosimetric files can be expanded to address a more comprehensive set of radionuclides without modifying the basic computational module. The methods and models build on the approach used in Publication 95 of the International Commission on Radiological Protection (ICRP 2004), Doses to Infants from Ingestion of Radionuclides in Mothers Milk . The software package allows input of case-specific information or judgments such as chemical form or particle size of an inhaled aerosol. The package is expected to be more suitable than ICRP Publication 95 for dose assessment for real events or realistic planning scenarios in which measurements of the mother s excretion or body burden are available.