A Green One-Pot Protocol for Regioselective Synthesis of New Substituted 7,8-Dihydrocinnoline-5(6H)-ones

Bulletin of the Korean chemical society

Jabbar Khalafy¹  Rolf H. Prager¹  Mehdi Rimaz Mahnaz Ezzati¹ 

关键词: Arylglyoxal;    1;    3-Cyclohexanedione;    Cinnoline;    Dimedone;    Regioselective;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A simple regioselective synthesis of cinnoline derivatives was achieved by a one-pot three component synthetic methodology. New substituted 7,8-dihydrocinnolin-5(6H)-ones are prepared via one-pot three component reaction of arylglyoxals with 1,3-cyclohexanedione and dimedone in the presence of hydrazine hydrate in moderate to good yields.

【 授权许可】

Unknown