Comparison of 18F-FDG PET and MRI in Assessment of Uterine Smooth Muscle Tumors

Journal of Nuclear Medicine

Yoshiaki Imamura¹  Narufumi Suganuma¹  Tetsuji Kurokawa¹  Tetsuya Tsujikawa¹  Hidehiko Okazawa¹  Tatsuro Tsuchida¹  Yoshio Yoshida¹  Yoko Sawamura¹  Akiko Shinagawa¹  Fumikazu Kotsuji¹ 

关键词: genitourinary;    oncology;    PET;    MRI;    PET/MRI;    ¹⁸F-FDG-PET;    uterine smooth muscle tumors;   

DOI  :  10.2967/jnumed.107.047142

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

The purpose of this study was to prospectively determine whether combined MRI and 18F-FDG PET is more accurate than MRI in assessing nonbenign uterine smooth muscle tumors (USMTs). Methods: Seventy patients (mean age, 49 ± 10 y; range, 28–77 y) suspected of having nonbenign USMTs underwent both MRI and 18F-FDG PET before surgery. Results were evaluated using receiver-operating-characteristic (ROC) analyses and the Cochran Q test. Results: The area under the ROC curve for MRI with 18F-FDG PET was significantly higher than that for MRI (0.97 vs. 0.89, P < 0.05). Although multiple comparisons using the Cochran Q test were not significant, the sensitivity, specificity, and accuracy for MRI with 18F-FDG PET with probable nonbenign USMT cases considered to be positive were higher than those for MRI (93.3% vs. 73.3%; 92.7% vs. 85.5%; and 92.9% vs. 82.9%, respectively). Conclusion: MRI with 18F-FDG PET is useful in assessing nonbenign USMTs, as compared with MRI.

【 授权许可】

Unknown