期刊论文详细信息
Journal of the Korean Chemical Society | |
Oxidative Cyclisation Based One-Pot Synthesis of 3-Substituted[1,2,4]triazolo[4,3-b]pyridazines Using Me4NBr/Oxone | |
Rajendran Senthil Kumaran1  Jayaraman Sembian Ruso1  Rajendiran Nagappan1  | |
关键词: Oxone; Aromatic aldehyde; | |
DOI : | |
学科分类:化学(综合) | |
来源: Korean Chemical Society | |
【 摘 要 】
A facile one-pot syhthesis of 3-substituted triazolopyridazine and thieno-triazolopyridazine derivatives is described. This protocol involves the preparation of heteroaryl hydrazone from the aldehyde and pyridazinohydrazine derivative followed by subjecting the intermediate directly to oxidative cyclization to assemble the desired 1,2,4-triazloe moiety by employing the mixture of Me4NBr and oxone. This condition is efficient and is able to tolerate wide range of functional groups.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010188195ZK.pdf | 341KB | download |