Recent Advances in the Oxone-Mediated Synthesis of Heterocyclic Compounds

Molecules

Eder J. Lenardão¹  Raquel G. Jacob¹  Filipe Penteado¹  Daniela R. Araujo¹  Helen A. Goulart¹  Gelson Perin¹ 

[1] Laboratório de Síntese Orgânica Limpa-LASOL-CCQFA, Universidade Federal de Pelotas-UFPel, P.O. Box 354, Pelotas 96010-900, RS, Brazil;

关键词: Oxone;    oxidant;    heterocycles;    green chemistry;   

DOI  :  10.3390/molecules26247523

来源: DOAJ

【 摘 要 】

Oxone is a commercially available oxidant, composed of a mixture of three inorganic species, being the potassium peroxymonosulfate (KHSO₅) the reactive one. Over the past few decades, this cheap and environmentally friendly oxidant has become a powerful tool in organic synthesis, being extensively employed to mediate the construction of a plethora of important compounds. This review summarizes the recent advances in the Oxone-mediated synthesis of N-, O- and chalcogen-containing heterocyclic compounds, through a wide diversity of reactions, starting from several kinds of substrate, highlighting the main synthetic differences, advantages, the scope and limitations.

【 授权许可】

Unknown