Studies on Some Bioactive 1,1-Bis(2-benzylidene-5-aryliden-1,3-thiadiazolidin-4-one)cyclopropane

Journal of the Korean Chemical Society

Sachi Singh¹  Amit Chawla¹  Nidhi Chaudhary¹  Hemant Panwar¹ 

关键词: Bis-phenylarylidinylthiadiazolidinone cyclopropane;    Antifungal;    Antibacterial;    Acute toxicity;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Some novel heterocyclic derivatives of 1,1-bis(2-phenyl-5-arylidine-1,3-thiadiazolidin-4-one)cyclopropane 4(a-i) have been synthesized from cyclopropane dicarboxylic acid and substituted thiadiazole moieties. All the synthesized compounds have been characterized by elemental and spectral (I.R., 1H-NMR, Mass) analysis. Furthermore, above said compounds were screened for their antifungal and antibacterial activities. Compound 4c was found the most potent one which further evaluated for lesser toxicity test.

【 授权许可】

Unknown