Technical Considerations in Brain Amyloid PET Imaging with 18F-Florbetapir

Journal of Nuclear Medicine Technology

LisaAnn Trembath¹  Michael D. Devous Sr.¹  Maureen Newell¹ 

[1] Avid Radiopharmaceuticals, Inc., Philadelphia, Pennsyvania Avid Radiopharmaceuticals, Inc., Philadelphia, Pennsyvania Avid Radiopharmaceuticals, Inc., Philadelphia, Pennsyvania

关键词: florbetapir;    PET;    brain imaging;    amyloid;    technical;   

DOI  :  10.2967/jnmt.115.156679

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Technical factors play a critical role in the production of best-quality amyloid PET images for interpretation. This article provides specific instructions and general technical information about PET brain scanning of β-amyloid neuritic plaques. The focus of tracer-specific information will be on 18F-florbetapir (indications, contraindications, dosing, administration, uptake time, scanning time, acquisition, processing, biodistribution, radiation dose, adverse events, and display). General scanning information relevant to all amyloid-imaging agents will be also be presented (e.g., mechanism of uptake, safe handling, positioning, prevention of patient motion, processing, and artifacts).

【 授权许可】

Unknown