Journal of Nuclear Medicine Technology | |
Measurement of 18F-FDG Concentrations in Blood Samples: Comparison of Direct Calibration and Standard Solution Methods | |
Arthur van Lingen1  Henri N.J.M. Greuter1  Eric J.F. Franssen1  Ronald Boellaard1  Adriaan A. Lammertsma1  | |
关键词: blood samples; activity concentration; 18F-FDG; dose calibrator; well counter; | |
DOI : | |
学科分类:医学(综合) | |
来源: Society of Nuclear Medicine | |
【 摘 要 】
Objective: The purpose of this study was to compare the accuracy and reliability of 2 well counter methods for measuring the activity concentration of 18F-FDG in blood samples.Methods: Three to 5 blood samples from 154 patient studies were weighed and measured in a well counter. The 18F-FDG activity concentration was derived using, first, a direct calibration factor to convert measured well counter readings into activity concentration and, second, a comparison of measured counts with those of a specified standard solution.Results: The ratio between the activity concentration results of the 2 methods was 0.996 ± 0.033, indicating that the methods provided equal results.Conclusion: Because the standard solution method is more prone to human error, less reproducible, and more labor intensive, preference should be given to the direct calibration method.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010179514ZK.pdf | 158KB | download |