Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors

PLOS Pathogens

Nicholas A. Meanwell¹  Zeyu Lin¹  Joseph Cantone¹  Mark Cockett¹  Zheng Liu¹  Tian Yuan¹  Alicia Regueiro-Ren¹  Mark Krystal¹  Hao Lu¹  Ira B. Dicker¹  Dieter Drexler¹  Beata Nowicka-Sans¹  Hong Yang¹  Max Lataillade¹  Tricia Protack¹ 

关键词: HIV-1;    Proteases;    Peptides;    Serine proteases;    HIV;    Chemical dissociation;    293T cells;    Crystal structure;   

DOI  :  10.1371/journal.ppat.1005990

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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