期刊论文详细信息
PLOS Pathogens | |
Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability | |
Kacie Rice1  Timothy Palzkill1  Shrenik C. Mehta1  | |
关键词: Hydrolysis; Antibiotic resistance; Antibiotics; Enzymes; Substitution mutation; Thermal stability; Penicillin; Enzyme kinetics; | |
DOI : 10.1371/journal.ppat.1004949 | |
学科分类:生物科学(综合) | |
来源: Public Library of Science | |