Crystal Structure of the Gamma-2 Herpesvirus LANA DNA Binding Domain Identifies Charged Surface Residues Which Impact Viral Latency

PLOS Pathogens

Chantal Beauchemin¹  Maria A. Carrondo¹  Shijun Li¹  Kenneth M. Kaye¹  Sofia A. Cerqueira¹  Colin E. McVey¹  Marta Pires de Miranda¹  Bruno Correia¹  J. Pedro Simas¹  Rajesh Ponnusamy¹  Thomas R. Schneider¹  Lénia Rodrigues¹ 

关键词: Viral persistence and latency;    DNA-binding proteins;    Glutathione chromatography;    B cells;    DNA structure;    Dimers (Chemical physics);    Crystal structure;    Phosphates;   

DOI  :  10.1371/journal.ppat.1003673

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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