Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41

PLOS Pathogens

Davide Corti¹  Winfried Weissenhorn¹  Federica Sallusto¹  Antonio Lanzavecchia¹  David Lutje Hulsik¹  Gloria Agatic¹  Lara Mainetti¹  Robin Weiss¹  Victor Buzon¹  Andreas Hinz¹  Chiara Silacci¹  Mike S. Seaman¹  Fabrizia Vanzetta¹  Charles Sabin¹  Gabriella Scarlatti¹ 

关键词: HIV-1;    Antibodies;    Membrane fusion;    Enzyme-linked immunoassays;    Crystal structure;    Cell fusion;    Somatic mutation;    Cell membranes;   

DOI  :  10.1371/journal.ppat.1001195

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown