Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo-β-lactamase detection on multidrug-resistant Acinetobacter baumannii

Revista da Sociedade Brasileira de Medicina Tropical

Martini, Rosiéli¹  Mayer, Letícia Eichstaedt¹  Roehrs, Magda Cristina Souza Marques¹  Kempfer, Cláudia Barbisan¹  Tizotti, Maisa Kräulich¹  Universidade Federal de Santa Maria, Santa Maria¹  Hörner, Rosmari¹ 

关键词: Drug resistance;    Acinetobacter baumannii;    Microbial sensitivity tests;   

DOI  :  10.1590/S0037-86822012000200021

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: Metallo-β-lactamase (MBL) has been reported all over the world.METHODS: The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concentration (MIC) for multidrug-resistant Acinetobacter baumanni strains.RESULTS: MPA significantly inhibited growth of the strains.CONCLUSIONS: The use of MPA can affect the results in phenotypic methods of MBL detection.

【 授权许可】

Unknown