Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo-β-lactamase detection on multidrug-resistant Acinetobacter baumannii

Revista da Sociedade Brasileira de Medicina Tropical

Letícia Eichstaedt Mayer¹  Rosmari Hörner¹  Maisa Kräulich Tizotti¹  Rosiéli Martini¹  Magda Cristina Souza Marques Roehrs¹  Cláudia Barbisan Kempfer¹ 

[1] ,Universidade Federal de Santa Maria Centro de Ciências da Saúde Departamento de Análises Clínicas e ToxicológicasSanta Maria RS

关键词: Drug resistance;    Acinetobacter baumannii;    Microbial sensitivity tests;    Resistência a medicamentos;    Acinetobacter baumannii;    Testes de sensibilidade microbiana;   

DOI  :  10.1590/S0037-86822012000200021

来源: SciELO

【 摘 要 】

INTRODUCTION: Metallo-β-lactamase (MBL) has been reported all over the world. METHODS: The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concentration (MIC) for multidrug-resistant Acinetobacter baumanni strains. RESULTS: MPA significantly inhibited growth of the strains. CONCLUSIONS: The use of MPA can affect the results in phenotypic methods of MBL detection.

【 授权许可】

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