Co-infection and risk factors of tuberculosis in a Mexican HIV+ population

Revista da Sociedade Brasileira de Medicina Tropical

Zenteno-Cuevas, Roberto¹  Hospital Civil L. F., Xalapa, México¹  Universidade Veracruzana, Xalapa, México¹  Morales-Romero, Jaime¹  Cuevas, Betzaida¹  Montes-Villaseñor, Evangelina¹  Coronel-Martín del Campo, Gastón¹ 

关键词: Tuberculosis;    HIV;    Risk factors;    Co-infection;   

DOI  :  10.1590/S0037-86822011005000034

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: The situation of tuberculosis (TB) is being modified by the human immunodeficiency virus (HIV), which is increasing the occurrence of new cases and the generation of drug resistant strains, affecting not only the people infected with HIV, but also their close contacts and the general population, conforming a serious public health concern. However, the magnitudes of the factors associated to this co-infection differ considerably in relation to the population groups and geographical areas.METHODS: In order to evaluate the prevalence and risk factors for the co-infection of tuberculosis (TB) in a population with human immunodeficiency virus (HIV+) in the Southeast of Mexico, we made the analysis of clinical and epidemiological variables and the diagnosis of tuberculosis by isolation of mycobacteria from respiratory samples.RESULTS: From the 147 HIV+ individuals analyzed, 12 were culture positive; this shows a prevalence of 8% for the co-infection. The only variable found with statistical significance for the co-infection was the number of CD4-T < 200 cells/mm3, OR 13 (95%, CI 2-106 vs 12-109).CONCLUSIONS: To our knowledge this is the first report describing the factors associated with tuberculosis co -infection with HIV in a population from Southern Mexico. The low number of CD4 T-cells was the only variable associated with the TB co-infection and the rest of the variables provide scenarios that require specific and particular interventions for this population group.

【 授权许可】

Unknown