Longitudinal clinical and serological survey of abdominal angiostrongyliasis in Guaporé, southern Brazil, from 1995 to 1999

Revista da Sociedade Brasileira de Medicina Tropical

Agostini, Aventino Alfredo¹  Morassutti, Alessandra¹  Schulz-Key, Hartwig¹  Aguiar, Luís Felipe¹  Eberhard Karls Universität, Tübingen¹  Silva, Ana Cristina Aramburu da¹  Maurer, Rafael Lucyk¹  Goulart, Aline Hamilton¹  Ludwig-Maximilians-Universität München, Munich, Germany¹  Universidade de Passo Fundo¹  Graeff-Teixeira, Carlos¹  Oliveira, Fernanda Teixeira dos Santos¹  Sievers-Tostes, Charlotte¹  Instituto de Patologia de Passo Fundo, Passo Fundo¹  Zanini, Graziela Maria¹  Garrido, Cinara Tentardini¹  Pontificia Universidade Católica do Rio Grande do Sul¹  Geiger, Stefan¹  Rodriguez, Rubens¹  Bered, Patrícia Leão¹  Abrahms-Sandi, Elizabeth¹  Brum, Charles de Ornellas¹  Laitano, Antonio Carlo¹ 

关键词: Abdominal angiostrongyliasis;    Angiostrongylus costaricensis;    Abdominal pain;    Eosinophilic gastroenteritis;    Zoonosis;   

DOI  :  10.1590/S0037-86822005000400006

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Abdominal angiostrongyliasis is a zoonotic infection caused by Angiostrongylus costaricensis, a nematode with an intra-vascular location in the mesentery. Our objective was to address several aspects of the natural history of this parasitosis, in a longitudinal clinical and seroepidemiological study. A total of 179 individuals living in a rural area with active transmission in southern Brazil were followed for five years (1995-1999) resulting in yearly prevalence of 28.2%, 4.2%, 10%, 20.2% and 2.8% and incidences of 0%, 5.9%, 8% and 1.5%, respectively. Both men and woman were affected with higher frequencies at age 30-49 years. In 32 individuals serum samples were collected at all time points and IgG antibody reactivity detected by ELISA was variable and usually persisting not longer than one year. Some individual antibody patterns were suggestive of re-infection. There was no association with occurrence of abdominal pain or of other enteroparasites and there was no individual with a confirmed (histopathologic) diagnosis. Mollusks were found with infective third-stage larvae in some houses with an overall prevalence of 16% and a low parasitic burden. In conclusion, abdominal angiostrongyliasis in southern Brazil may be a frequent infection with low morbidity and a gradually decreasing serological reactivity.

【 授权许可】

Unknown