Longitudinal clinical and serological survey of abdominal angiostrongyliasis in Guaporé, southern Brazil, from 1995 to 1999

Revista da Sociedade Brasileira de Medicina Tropical

Carlos Graeff-teixeira¹  Aline Hamilton Goulart¹  Charles De Ornellas Brum¹  Antonio Carlo Laitano¹  Charlotte Sievers-tostes¹  Graziela Maria Zanini¹  Patrícia Leão Bered¹  Alessandra Morassutti¹  Stefan Geiger²  Elizabeth Abrahms-sandi²  Fernanda Teixeira Dos Santos Oliveira¹  Rafael Lucyk Maurer¹  Luís Felipe Aguiar¹  Cinara Tentardini Garrido¹  Ana Cristina Aramburu Da Silva¹  Rubens Rodriguez²  Hartwig Schulz-key²  Aventino Alfredo Agostini² 

[1] ,Pontificia Universidade Católica do Rio Grande do Sul Faculdade de Biociências Laboratório de Biologia Parasitária

关键词: Abdominal angiostrongyliasis;    Angiostrongylus costaricensis;    Abdominal pain;    Eosinophilic gastroenteritis;    Zoonosis;    Angiostrongilíase abdominal;    Angiostrongylus costaricensis;    Dor abdominal;    Gastroenterite eosinofílica;    Zoonose;   

DOI  :  10.1590/S0037-86822005000400006

来源: SciELO

【 摘 要 】

Abdominal angiostrongyliasis is a zoonotic infection caused by Angiostrongylus costaricensis, a nematode with an intra-vascular location in the mesentery. Our objective was to address several aspects of the natural history of this parasitosis, in a longitudinal clinical and seroepidemiological study. A total of 179 individuals living in a rural area with active transmission in southern Brazil were followed for five years (1995-1999) resulting in yearly prevalence of 28.2%, 4.2%, 10%, 20.2% and 2.8% and incidences of 0%, 5.9%, 8% and 1.5%, respectively. Both men and woman were affected with higher frequencies at age 30-49 years. In 32 individuals serum samples were collected at all time points and IgG antibody reactivity detected by ELISA was variable and usually persisting not longer than one year. Some individual antibody patterns were suggestive of re-infection. There was no association with occurrence of abdominal pain or of other enteroparasites and there was no individual with a confirmed (histopathologic) diagnosis. Mollusks were found with infective third-stage larvae in some houses with an overall prevalence of 16% and a low parasitic burden. In conclusion, abdominal angiostrongyliasis in southern Brazil may be a frequent infection with low morbidity and a gradually decreasing serological reactivity.

【 授权许可】

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