Clinical profile and warning sign finding in children with severe dengue and non-severe dengue

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Adam, A.S.^1 ; Pasaribu, S.^1 ; Wijaya, H.^1 ; Pasaribu, A.P.^1,2

Department of Pediatrics, Medical Faculty, Universitas Sumatera Utara, H.Adam Malik General Hospital, Medan, Indonesia^1

ClinicalResearch Unit, Universitas Sumatera Utara Hospital, Medan, Indonesia^2

关键词: Abdominal pain;    Clinical manifestation;    Dengue fevers;    Fluid accumulation;    Medical record;    Viral disease;    Warning signs;    White cell;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012038/pdf
DOI  :  10.1088/1755-1315/125/1/012038

来源: IOP

【 摘 要 】

Dengue fever is one of the most important emerging vector-borne viral diseases. Approximately 500,000 out of 100 million cases develop to severe dengue infection. Patient with severe dengue (SD) can be predicted by clinical profile, laboratory and warning sign which could be saved by early interventions.This was a retrospective descriptive-analytic study to investigate clinical manifestations, laboratory and warning signs ofchildren with dengue infection in Haji Adam Malik hospital during January 2014-May 2016. Through medical records, we had selected 140 cases which fulfilled research criteria.Cases were classified as SD (n=28) and NSD (n=112). Most common clinical manifestations for NSD were abdominal pain (39.3%), myalgia (39.3%), headache (37.1%), mucosal bleeding (36.4%) while for SD were shock (15.7%), mucosal bleeding (15.7%), clinical fluid accumulation (15%), shortness of breath (14.3%). SGPT >1000IU/L (5 cases), SGOT >1000IU/L (9 cases), PT (10 cases) and aPTT (16 cases) were abnormal in SD. Severe dengue was frequently found in the range of white cell count 1000-4000/L and platelet count 20,000-50,000mm/uL. Clinical manifestations, warning sign, and laboratoryfinding, were different between SD and NSD.