Usefulness of routine investigation of fungal infection through bronchoscopy in patients HIV-infected or not in a general hospital, reference to AIDS

Revista da Sociedade Brasileira de Medicina Tropical

Caiuby, Maria Julieta M.¹  Universidade Federal do Rio de Janeiro, Rio de Janeiro¹  Lazzarini-de-Oliveira, Luiz Claudio¹  Arantes, Adriana A.¹ 

关键词: Fungus;    Bronchoscopy;    Bronchoalveolar lavage;    HIV infection;    AIDS;   

DOI  :  10.1590/S0037-86821999000300006

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

The diagnostic yields and the spectrum of pulmonary fungal infection obtained in samples collected by fiberoptic bronchoscopy from HIV-positive and HIV-negative patients were evaluated from 1990 to 1995. A total of 1943 bronchoscopies were performed during this period, 47% in the HIV-positive group and 53% in the HIV- negative group. Of 908 HIV-positive patients, 38 (4%) had a fungus isolated from the pulmonary sample whereas of 1035 HIV-negative patients, only 4 (0.2%) had a fungus isolated. Histoplasmosis and Cryptococcosis were more frequently found in HIV-positive than in HIV-negative patients (p < 0.001). Paracoccidioides brasiliensis was found in only 3 patients, all of them immunocompetent. The study demonstrated that, despite the low yields, the HIV-positive group may benefit from routine screening for fungal elements in specimens obtained by fiberoptic bronchoscopy.

【 授权许可】

Unknown