Investigation of the response to the enterobacterial common antigen after typhoid vaccination

Revista da Sociedade Brasileira de Medicina Tropical

Milhomem, Arlete M.¹  Suassuna, ítalo¹  Universidade Federal do Rio de Janeiro, Brasil¹ 

关键词: Typhoid fever;    Vaccine;    Salmonella typhi;    Enterobacterial common antigen;    O and H antigens;   

DOI  :  10.1590/S0037-86821987000100002

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Antibodies against the Salmonella typhi enterobacterial common antigen (ECA) and the O and H antigens were investigated in sera from healthy male subjects who had been previously vaccinated with the typhoid vaccine. No serological response to ECA was observed. Sera from subjects not previously vaccinated presented titers of ECA hemagglutinins which quantitatively were related to the presence ofH titers, but not to O agglutinins but with no statistical significance. The results are discussed in relation to the possible protective immunological mechanisms in typhoid fever.

【 授权许可】

Unknown