Comparison of the Light Charged Particles on Scatter Radiation Dose in Thyroid Hadron Therapy

Journal of Biomedical Physics and Engineering

AA Mowlavi¹  M Azizi¹ 

关键词: Hadron therapy;    thyroid gland;    secondary particles;    photon and neutron flux;    energy deposition;   

DOI  :  

学科分类：生物科学（综合）

来源: Shiraz University of Medical Sciences

【 摘 要 】

Bachground:Hadron therapy is a novel technique of cancer radiation therapy which employs charged particles beams,1 H and light ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal treatment, sparing better the healthy tissues located in proximity of the tumor and allowing a higher control of the disease. Objective:As it is well known, these light particles can interact with nuclei in the tissue, and produce the different secondary particles such as neutron and photon. These particles can damage specially the critical organs behind of thyroid gland.Methods:In this research, we simulated neck geometry by MCNPX code and calculated the light particles dose at distance of 2.14 cm in thyroid gland, for different particles beam:1 H,2 H,3 He, and4 He. Thyroid treatment is important because the spine and vertebrae is situated right behind to the thyroid gland on the posterior side.Results:The results show that2 H has the most total flux for photon and neutron, 1.944E-3 and 1.7666E-2, respectively. Whereas1 H and3 He have best conditions, 8.88609E-4 and 1.35431E-3 for photon, 4.90506E-4 and 4.34057E-3 for neutron, respectively. The same calculation has obtained for energy depositions for these particles. Conclusion:In this research, we investigated that which of these light particles can deliver the maximum dose to the normal tissues and the minimum dose to the tumor. By comparing these results for the mentioned light particles, we find out1 H and3 He is the best therapy choices for thyroid glands whereas2 H is the worst.

【 授权许可】

Unknown