Geant4 studies of the CNAO facility system for hadrontherapy treatment of uveal melanomas

20th International Conference on Computing in High Energy and Nuclear Physics

物理学;计算机科学

Rimoldi, A.^1,2 ; Piersimoni, P.^1,2,3 ; Pirola, M.^1 ; Riccardi, C.^1

Department of Physics, University of Pavia, via Bassi 6, Pavia

27100, Italy^1

INFN Pavia, via Bassi 6, Pavia

27100, Italy^2

Fondazione CNAO, Strada privata Campeggi, Pavia

27100, Italy^3

关键词: Beam characteristics;    Geant4 toolkits;    Hadron therapy;    MC simulation;    Ocular melanoma;    Passive elements;    Transport beam lines;    Treatment planning systems;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/513/2/022028/pdf
DOI  :  10.1088/1742-6596/513/2/022028

学科分类：计算机科学（综合）

来源: IOP

【 摘 要 】

The Italian National Centre of Hadrontherapy for Cancer Treatment (CNAO -Centro Nazionale di Adroterapia Oncologica) in Pavia, Italy, has started the treatment of selected cancers with the first patients in late 2011. In the coming months at CNAO plans are to activate a new dedicated treatment line for irradiation of uveal melanomas using the available active beam scan. The beam characteristics and the experimental setup should be tuned in order to reach the necessary precision required for such treatments. Collaboration between CNAO foundation, University of Pavia and INFN has started in 2011 to study the feasibility of these specialised treatments by implementing a MC simulation of the transport beam line and comparing the obtained simulation results with measurements at CNAO. The goal is to optimise an eye-dedicated transport beam line and to find the best conditions for ocular melanoma irradiations. This paper describes the Geant4 toolkit simulation of the CNAO setup as well as a modelised human eye with a tumour inside. The Geant4 application could be also used to test possible treatment planning systems. Simulation results illustrate the possibility to adapt the CNAO standard transport beam line by optimising the position of the isocentre and the addition of some passive elements to better shape the beam for this dedicated study.