Results and approach of lung metastasectomy in the National Institute of Oncology and Radiobiology of Cuba

Revista Cubana de Cirugía

Paredes López, Dagmar¹  Collado Otero, Juan Carlos¹  Danta Fundora, Deborah¹  Instituto Nacional de Oncología y Radiobiología (INOR), La Habana, Cuba¹ 

关键词: Lung metastasis;    lung metastasectomy.;   

DOI  :  

学科分类：外科医学

来源: SciELO

【 摘 要 】

INTRODUCTION. The aim of this paper was to identify the prognostic factors related to higher survival after lung metastasectomy for all types of primary tumor performed in the National Institute of Oncology and Radiobiology of Cuba.METHODS. An ambispective nonrandomized study was undertaken. The study group was composed of patients with lung metastases of intra- or extrapulmonary origin.RESULTS. In the univariate analysis, the number (p = 0.004) and size (p = 0.02) of the metastasis, as well as the disease free time (p = 0.012) proved to be positive predictive indicators of a longer disease free interval and a higher global survival at 3 years. The approach route and the resection technique used did not influence either on global survival at 3 years or on the disease free interval, provided that all the metastases were resected (p > 0.05). The resection technique allowed the exeresis of all the detectable lesions with a margin of sound tissue, and lung parenchyma was preserved at the most. The adequate volume and the resection technique depended on the number, size and localization of the lesions. The minimum time of follow-up was 3 years.CONCLUSIONS. The disease free interval was identified as the most important factor for prognosis. The survival analysis permitted to stratify the patients into risk groups according to the progression of the tumor and on the basis of the size and amount of lesions and of the disease free interval after the excision of the primary tumor.

【 授权许可】

Unknown