期刊论文详细信息
Revista Brasileira de Farmacognosia | |
Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae) | |
University of Aberdeen, Scotland1  Tabriz University of Medical Sciences, Tabriz, Iran1  University of Ulster at Coleraine, Northern Ireland1  Rezazadeh, H.1  Delazar, A.1  Nazemiyeh, H.1  Sarker, S.D.1  Nahar, L.1  Talischi, B.1  | |
关键词: Chrozophora tinctoria; Euphorbiaceae; flavonoid; flavone; glycoside; quercetin; apigenin; rutin; chrozophorin; DPPH.; | |
DOI : 10.1590/S0102-695X2006000300002 | |
来源: Sociedade Brasileira de Farmacognosia | |
【 摘 要 】
Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Chrozophora tinctoria (Euphorbiaceae) yielded five flavonoid glycosides, quercetin 3-O-rutinoside (1, rutin), acacetin 7-O-rutinoside (2), apigenin 7-O-b-D-[(6-p-coumaroyl)]-glucopyranoside (3), apigenin 7-O- b-D-glucopyranoside (4) and apigenin 7-O-b-D-[6-(3,4-dihydroxybenzoyl)]-glucopyranoside (named, chrozophorin, 5), the last one being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques. The free-radical scavenging activity of the methanol extract (RC50 = 2.24 x 10-1 mg/mL) as well as the isolated compounds (1-5) (RC50 = 4.38 x 10-3, 2.26 x 10-2, 7.69 x 10-4, 8.71 x 10-3 and 3.19 x 10-4 mg/mL, respectively) were assessed by the DPPH assay.【 授权许可】
Unknown
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