Changes in respiratory function in Pembroke Welsh Corgi dogs withdegenerative myelopathy

Journal of Veterinary Medical Science

Miyoko SAITO³  Yui KOBATAKE¹  Hiroki SAKAI²  Kazuya KUSHIDA⁴  Sanae SHIBATA²  Kanae OYAKE²  Sadatoshi MAEDA²  Hiroaki KAMISHINA²  Osamu YAMATO⁴ 

[1] The United Graduate School of Veterinary Sciences, Gifu University, 1�?1 Yanagido, Gifu 501�?1193, Japan;Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1�?1 Yanagido, Gifu 501�?1193, Japan;Department of Surgery II, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa 229�?8501, Japan;Laboratory of Clinical Pathology, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1�?21�?24 Kohrimoto, Kagoshima 890�?0065, Japan

关键词: abdominal breathing pattern;    arterial blood gas analysis;    canine degenerative myelopathy;    hypoventilation;    hypoxemia;   

DOI  :  10.1292/jvms.15-0521

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(15)Cited-By(1)Canine degenerative myelopathy (DM) is characterized by progressive degeneration of thespinal cord. Although atrophic changes in the intercostal muscles were previously reportedin the late stage of DM in Pembroke Welsh Corgis (PWCs), changes in respiratory functionhave not yet been examined. In the present study, we performed an arterial blood gasanalysis and measured respiratory movements over progressive disease stages to documentchanges in respiratory function in DM-affected PWCs. We found that respiratory dysfunctionprogressed during the later stages of DM and correlated with a change in respiratorymovement to the abdominal breathing pattern. These results suggested that hypoventilationoccurred due to dysfunctional changes in the intercostal muscles and resulted in hypoxemiain the later stages of DM.

【 授权许可】

Unknown