Hyperferritinemia is associated with short survival time in dogs withmulticentric lymphoma

Journal of Veterinary Medical Science

Fumio HOSHI¹  Yasutomo HORI¹  Naoyuki ITO¹  Seishiro CHIKAZAWA¹  Kazutaka KANAI¹ 

[1] Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23�?35�?1 Higashi, Towada, Aomori 034�?8628, Japan

关键词: canine;    ferritin;    lymphoma;    prognostic factor;   

DOI  :  10.1292/jvms.14-0314

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(20)In the present study, we examined the relationship between serum ferritin concentrationbefore treatment and survival time in dogs with multicentric lymphoma. Eighteen dogs withmulticentric lymphoma were enrolled in the study. When the dogs were classified into highand low ferritin groups on the basis of their serum ferritin concentration (3,000ng/ml cut-off value), the median survival time of dogswith high concentrations (�?3,000 ng/ml, n=7) was 40days, whereas it was 360 days among dogs with low concentrations (<3,000ng/ml, n=11). This difference was statisticallysignificant (P=0.001). This finding suggests that the initial high levelof serum ferritin indicates short survival time in dogs with multicentric lymphoma.Large-scale research is necessary to confirm this finding.

【 授权许可】

Unknown