Factors Influencing Measurement of Serum Iron Concentration in Dogs: Diurnal Variation and Hyperferritinemia

Journal of Veterinary Medical Science

Fumio HOSHI¹  Yasutomo HORI¹  Koichi ORINO²  Seiichi HIGUCHI¹  Naoyuki ITO¹  Seishiro CHIKAZAWA¹  Kazutaka KANAI¹  Kiyotaka WATANABE² 

[1] Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23�?35�?1 Higashi, Towada, Aomori 034�?8628, Japan;Laboratory of Biochemistry, School of Veterinary Medicine, Kitasato University, 23�?35�?1 Higashi, Towada, Aomori 034�?8628, Japan

关键词: canine;    diurnal variation;    ferritin;    serum iron;   

DOI  :  10.1292/jvms.13-0286

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(23)Cited-By(1)We evaluated diurnal variation and hyperferritinemia as factors that influence the values of serum iron concentration in dogs, using the International Committee for Standardization in Hematology (ICSH) colorimetric method. Serum iron levels were significantly higher in the morning than in the evening in 6 clinically healthy beagle dogs, and the maximum decrease in serum iron concentration was 47.3%. Moreover, the change in serum iron concentrations in 22 clinical canine cases with various serum ferritin levels was evaluated by immunoprecipitation of ferritin. The rate of decline in the serum iron concentrations positively correlated with serum ferritin levels (r=0.48, P=0.024). These results show that it is necessary to consider the sampling time and serum ferritin level for accurate interpretation of serum iron concentrations in dogs.

【 授权许可】

Unknown