Immunological Cross-Reaction between Lactoferrin and Transferrin

Journal of Veterinary Medical Science

Sayuri YAHIKOZAWA¹  Shinji YAMAMOTO¹  Kouichi ORINO¹  Kiyotaka WATANABE¹ 

关键词: cross-reaction;    lactoferrin;    transferrin;   

DOI  :  10.1292/jvms.57.519

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(22)Cited-By(10)Hardly any or only a weak immunological cross-reaction was found between native lactoferrin (Lf) and transferrin (Tf). However, when these iron-binding proteins were denatured with sodium dodecyl sulfate and dithiothreitol, a definite immunological cross-reaction was detected between them. These results indicate that although Lf and Tf are immunologically quite different from each other in their native forms, they have the common antigenic determinant(s) in their unfolded forms.

【 授权许可】

Unknown